Disodium cromoglycate in allergic respiratory disease.
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چکیده
منابع مشابه
X-ray analysis of disodium cromoglycate.
Disodium cromoglycate (I; DSCG) was introduced in 1968 for the treatment of bronchial asthma. Evidence concerning its principal effects and possible mode of action has been described at some length in the recent literature (Cox, 1971 ; Cox & Altoanyan, 1970). Crystals of the compound exhibit a remarkable reversible water absorption (Cox, Woodard & McCrone, 1971), the number of water molecules p...
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A CHEAPER PREPARATION OF DISODIUM CROMOGLYCATE IN THE TREATMENT OF ALLERGIC RHINITIS From Major N K Cooper FRCS(Ed), DLO, RAMC Sir, The clinical symptoms of allergic rhinitis are brought on in predisposed individuals during the pollen season by the release of histamine from mast cells in the nasal mucosal,2 following the combination of antigen with antibody at the surface of these cells• This p...
متن کاملDisodium cromoglycate in the treatment of chronic proctitis.
The effect of topical disodium cromoglycate (DSCG) has been examined in 30 patients with chronic active proctitis using a double-blind crossover trial. Each treatment period was four weeks and patients were given DSCG 200 mg by enema twice daily and 100 mg orally three times each day. Twenty-six patients completed the trial successfully, 14 responded to DSCG treatment, two improved with placebo...
متن کاملDisodium cromoglycate can inhibit virus-induced cytopathic effects in vitro.
Investigations showed: haemoglobin 12 8 g/dl; white cell count 11 3 x 109!l (11 300/mm3), with 15 % eosinophils; blood urea 10-3 mmol/I (62 mg/ 100 ml); blood glucose 5-4 mmol/l (98 mg/100 ml); and serum sodium 129 mmol(mEq)/l, potassium 5-2 mmol(mEq)/l, and chloride 97 mmol (mEq)/l. Chest and abdominal x-ray pictures were normal. Antinuclear factor and thyroid and parietal cell antibodies were...
متن کاملColumnar molecular aggregation in the aqueous solutions of disodium cromoglycate.
Stack, chimneylike, and threadlike assemblies have previously been proposed for the structure of disodium cromoglycate (DSCG) aggregates in aqueous solutions. The results of the synchrotron x-ray scattering investigations reported here reveal the formation of simple columnar assemblies with π-π stacking at a separation of 3.4 Å between the DSCG molecules. Lateral separation between the assembli...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.3.5822.353